Organ-Specific and Memory Treg Cells: Specificity, Development, Function, and Maintenance
نویسندگان
چکیده
منابع مشابه
Organ-Specific and Memory Treg Cells: Specificity, Development, Function, and Maintenance
Foxp3(+) regulatory T cells (Treg cells) are essential for establishing and maintaining self-tolerance, and also inhibit immune responses to innocuous environmental antigens. Imbalances and dysfunction in Treg cells lead to a variety of immune-mediated diseases, as deficits in Treg cell function contribute to the development autoimmune disease and pathological tissue damage, whereas overabundan...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2014
ISSN: 1664-3224
DOI: 10.3389/fimmu.2014.00333